Table 7

Results of haplotype analysis on LSA and SSA triads using the transmission disequilibrium test

A45AA432AL769LTDT (7 LSA trios)TDT (45 SSA trios)
c135G>Ac1296G>Ac2307T>GTRNTχ2p ValueTRNTχ2p Value
LSA, long segment aganglionosis; NT, chromosomes not transmitted; SSA, short segment aganglionosis; TR, chromosomes transmitted.
AGG512.670.1038819.570.00001
AAG303.000.08022.000.15
AAT00011.000.31
AGT00120.330.56
GAG110.001.00330.001.00
GGG202.000.15240.670.41
GAT022.000.163147.120.007
GGT077.000.0087206.260.41