Table 1

(A) Clinical and (B) pathological responses to neoadjuvant chemotherapy in BRCA1/2 carriers and non-carriers

AClinical complete responseLess than clinical complete responsep value
BRCA1/2 carriers101
BPathological complete responseLess than pathological complete responsep value
*Carriers were matched to controls on TNM stage and on closest age (means 44.1 and 44.3 years, p=0.95) and grade.
†Two carriers who had a clinical complete response were excluded from this analysis because they did not have any further surgery after neoadjuvant chemotherapy.
BRCA1/2 carriers†45