Frequencies of the minor alleles and haplotypes in the seven SNPs in the two genes*
| APOE | TGF-β1 | ||
|---|---|---|---|
| SNP | Frequency (%) | SNP | Frequency (%) |
| *Allele frequencies of SNPs are the frequencies of the rare alleles | |||
| †APOE haplotypes were reconstructed by the four SNPs in the order SNP1, SNP2, SNP3, SNP4. | |||
| ‡APOE haplotypes were defined by the two SNPs in the order SNP3, SNP4. | |||
| §TGF-β1 haplotypes were reconstructed according to the three SNPs in the order SNP5, SNP6, SNP8. | |||
| SNP1 | 35.7 | SNP5 | 31.1 |
| SNP2 | 39.9 | SNP6 | 2.1 |
| SNP3 | 14.9 | SNP8 | 27.3 |
| SNP4 | 8.7 | ||
| Haplotype† | Haplotype§ | ||
| CGTC | 32.9 | C-T | 0.9 |
| CGTT | 0.6 | C-C | 0.9 |
| CGCC | 0.8 | C+T | 20.5 |
| CATC | 1.1 | C+C | 47.8 |
| CATT | 0.1 | T-T | 0.2 |
| CACC | 0.1 | T-C | 0.2 |
| GGTC | 6.5 | T+T | 6.4 |
| GGTT | 7.4 | T+C | 23.1 |
| GGCC | 13.8 | ||
| GGCT | 0.1 | ||
| GATC | 35.2 | ||
| GATT | 0.7 | ||
| GACC | 0.7 | ||
| Haplotype‡ | |||
| CT | 0.4 | ||
| TT | 11.1 | ||
| TC | 68.1 | ||
| CC | 20.4 | ||