Table 1

N-ras mutations and MC1R variants in human spontaneous dysplastic naevi

Patient No	Gender	Age	Lesion (mm)	Location/ subtype	% of AM	Skin type	Naevus colour	N-ras mutation	MC1R variant
NA = information not available; % of AM = % of histologically characterised atypical melanocytes in the respective DMN lesion; subtype = histological subtype: CN = compound naevus, JN = junction naevus.
1	Female	33	6	Back CN	10	NA	Light brown	No	R151C
2	Female	49	NA	Upper leg CN	10	II	Brown	No	No
3	Female	39	9	Back CN	20	NA	Dark brown	No	No
4	Male	13	ND	Back CN	5	NA	Brown	No	No
5	Female	37	NA	Upper arm CN	5	NA	Brown	No	No
6	Male	29	5	Back CN	30	II	Dark brown	No	R151C
7	Male	55	3	Ear JN	40	NA	Dark brown	No	No
8	Male	19	NA	Breast CN	1	NA	NA	No	No
9	Female	26	NA	Back CN	5	NA	NA	No	D84E
10	Female	23	NA	NA CN	10	NA	NA	No	No
11	Male	35	4	Back CN	5	NA	Brown	No	No
12	Male	35	NA	Back CN	5	NA	Brown	No	No
13	Female	38	NA	Back CN	10	NA	NA	No	No
14	Female	27	5	Upper leg JN	20	NA	Brown	No	No
15	Male	54	4	Back CN	10	NA	Dark brown	No	No
16	Female	23	3	Upper leg JN	5	NA	Dark brown	No	V92M
17	Female	47	NA	Flank CN	5	NA	Brown	No	No
18	Female	33	NA	Back JN	10	NA	NA	CAA (Q) to AAA (K)	No
19	Female	19	NA	Sole CN	5	NA	NA	No	No