TNF −308 and LTA NcoI polymorphisms and stages of pneumoconiosis in coal miners
| TNF −308 | LTA NcoI | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 11 | 12 | 22 | 12 or 22 | p value* | 11 | 12 | 22 | p value | |
| *12 or 22 v 11. | |||||||||
| 1994 x ray grade, No | 158 | 52 | 2 | 54 | 18 | 91 | 101 | ||
| 0/0, % | 72.8 | 69.2 | 50.0 | 68.5 | 55.6 | 69.2 | 76.2 | ||
| 0/1, % | 15.2 | 13.5 | 50.0 | 14.8 | 22.2 | 17.6 | 11.9 | ||
| 1/0, % | 8.2 | 11.5 | 0.0 | 11.1 | 0.8 | 16.7 | 11.0 | 5.9 | 0.3 |
| 1/1 or 1/2, % | 3.2 | 5.8 | 0.0 | 5.6 | 5.5 | 2.2 | 5.0 | ||
| 2/1 or over, % | 0.6 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.0 | ||
| 1994 CT scan micronodule score, No | 157 | 52 | 2 | 54 | 18 | 90 | 101 | ||
| (mean (SD)) | 2.15 (2.84) | 1.67 (2.09) | 1.00 (1.41) | 1.65 (2.07) | 0.16 | 2.78 (2.56) | 1.49 (1.91) | 2.39 (3.17) | 0.03 |
| 1999 x ray grade, No | 154 | 49 | 1 | 50 | 17 | 86 | 99 | ||
| 0/0, % | 68.2 | 61.2 | 100 | 62.0 | 35.3 | 65.1 | 72.7 | ||
| 0/1, % | 8.4 | 8.2 | 0.0 | 8.0 | 17.7 | 10.5 | 5.1 | ||
| 1/0, % | 10.4 | 12.2 | 0.0 | 12.0 | 0.9 | 17.6 | 15.1 | 6.1 | 0.007 |
| 1/1 or 1/2, % | 11.0 | 16.3 | 0.0 | 16.0 | 29.4 | 9.3 | 12.1 | ||
| 2/1 or over, % | 2.0 | 2.1 | 0.0 | 2.0 | 0.0 | 0.0 | 4.0 | ||