Incidence of cystic fibrosis and CF heterozygosity among fetuses with echogenic bowel in Brittany, France (1991–2000)
| Fetuses with echogenic bowel | 142 |
|---|---|
| Affected fetuses | |
| Number | 14 |
| Incidence | 1/10 |
| Genotypes | |
| ΔF508/ΔF508 | 9 |
| ΔF508/4005+1G→A | 1 |
| ΔF508/3129del4 | 1 |
| ΔF508/Q220X | 1 |
| ΔF508/W1282X | 1 |
| ΔF508/1717-1G→A | 1 |
| CF incidence in the general population during the present study | 1/2987 |
| Risk of CF: echogenic bowel fetuses/general population | 294 |
| Heterozygous fetuses | |
| Number | 11 |
| Incidence | 1/13 |
| Mutations | |
| ΔF508 | 9 |
| G542X | 1 |
| R347H | 1 |
| CF heterozygosity in the general population during the present study | 1/28 |
| Risk of CF heterozygosity: echogenic bowel fetuses/general population | 2.2 |