Summary of major reported case series in LHON
| No of pedigrees | Median onset (y) | Male:female ratio | Visual recovery | Reference | |
|---|---|---|---|---|---|
| G3460A | 9 | 29 | 2.3 : 1 | 22% | 26 |
| 8 | 20 | 4.3 : 1 | 25% | 9 | |
| G11778A | 49 | 28 | 4.5 : 1 | 4% | 25 |
| 66 | 24 | 3.7 : 1 | 25% | 9 | |
| T14484C | 17 | 27 | 2.1 : 1 | 37% | 27 |
| 23 | 19 | 7.7 : 1 | 58% | 10 |