CO and other ocular malformations
| CO/ocular malformation | Frequency | Reference |
|---|---|---|
| Tongue of hair | 40 (34.2%) | 3 (two cases), 8,9,11 (two cases), 16 (two cases) 19–22,32,33,37,38,42,51,52 (three cases), 56–58 (three cases), 6062 (six cases), 63,66 (two cases), 67–69 |
| Absent eyelashes/eyebrows or alopecia of eyebrows | 34 (29.1%) | 3,4,10,11 (two cases), 14,18–20,16 (two cases), 21,25,32,37,39,42,45,48,49,60,51,52 (two cases), 58 (three cases), 61,63,66 (two cases), 67–69 |
| Coloboma of eyelid | 21 (17.9%) | 3,14,21,23,27,30,42,43,49,52 (two cases),56,58,60,62 (four cases),64,66,68 |
| Groove in frontal bone/furrow to forehead/temporal depression | 10 (8.5%) | 3, 8, 16, 19, 27, 59, 60, 63, 64, 68 |
| Microphthalmia | 25 (21.4%) | 55–58,3,12,4 (three cases),17–19 (two cases),20,21,63,36 (two cases),41–43,66 (two cases),52,69 |
| Anophthalmia | 7 (6.0%) | 3,4,34,45 (three cases),62 |
| Corneal opacification/corneal clouding/sclerocornea | 12 (10.3%) | 4, 16, 27, 33, 37, 43, 49, 58, 60, 62, 64, 67 |
| Microcornea/absence of the cornea/corneal epithelial defect | 3 (2.6%) | 16, 41, 58 |
| Abnormal anterior chamber/absence of the anterior structures | 6 (5.1%) | 11 (two cases),18,41,52,67,69 |
| Hypoplasia of the optic nerve/atrophy of optic nerve | 6 (5.1%) | 4 (two cases),11,24,25,52 |
| Symblepharon/oculopalpebral synechiae | 17 (14.5%) | 4,5,8,16,30,37,39,43,47,49,60 (two cases),61,62,64,65,68 |
| Orbital or corneal dermoid | 5, 27 | |
| Skin tag over left eye | 37 | |
| Coloboma unstated | 38 | |
| Ocular coloboma | 5, 21, 41 | |
| Cataracts | 41 | |