Table 3

Adjusted plasma fibrinogen levels (g/l) of different genotypes in smokers and non-smokers (men)

GenotypeNon-smokers (n=131)Smokers (n=60)
NoFBG3-150R2× 100 (p)NoFBG3-150R2× 100 (p)
−455G/A RFLP
 G/G−455 662.570.46 (NS)412.513.38  (NS)
 G/A−455 & A/A−455 642.69192.75
+1689T/G RFLP
 T/T+1689 662.570.37 (NS)402.468.76 (0.022)
 T/G+1689 & G/G+1689 642.69202.88
BclI RFLP
 B1B1 682.570.44 (NS)422.466.60 (0.049)
 B1B2 & B2B2 632.69182.82
TaqI RFLP
 T1T1 392.632.79 (NS)162.5718.10 (0.004)
 T1T2 652.69292.82
 T2T2 262.46142.14
T312A RFLP
 T312T312382.632.35 (NS)162.5716.28 (0.007)
 T312A312672.69302.75
 A312A312252.46142.19
  • 3-150 FBG = geometric means of plasma fibrinogen adjusted for age, BMI, and other significant covariates. NS: non-significant.