Table 1

Iron status in 545 probands homozygous for the C282Y mutation

Sex Age No Transferrin saturation (%) Serum ferritin (μg/l) Serum iron (μmol/l)
F<301168 (11.8)262 (104)37 (5.6)
[55–82][108–398][28–42]
M<302279.6 (16.7)598 (506)38.4 (8.8)
[51–98][83–2000][21–49]
NSNSNS
F<403079 (14.7)663 (944)37 (11.3)
[57–99][69–4000][14–62]
M<4010578.2 (15.5)1341 (1078)38.8 (7.8)
[34–100][240–4800][22–69]
NSp=0.02NS
F<505076.6 (14.6)588 (764)33.2 (6.6)
[54–95][36–3300][22–53]
M<5011782.5 (12.1)1822 (1672)38.4 (6.3)
[44–100][95–8890][22–51]
p=0.05p=0.0003p=0.055
F<605270 (16.9)847 (657)31.8 (6.4)
[27–96][77–2500][22–48]
M<607181.8 (12)2133 (1601)44.7 (25.2)
[47–97][450–5368][27–57]
p=0.001p=7.10−6 p=0.01
F>605475.8 (18.4)1649 (1525)36.3 (8.4)
[37–98][195–6680][14–55]
M>603379.6 (18)2349 (2059)38.8 (6)
[37–95][215–8800][28–49]
NSp=0.033NS
  • Transferrin saturation, serum ferritin, and serum iron values are expressed as means (SD) and range (NS = not significant).