Table 3

Summary of potential tumour suppressor loci on chromosome 14

Tumour suppressor locusProposed cytogenetic positionsMolecular definitionsReferences
Colorectal carcinoma14q32D14S65-D14S250See text
D14S20-qter
Malignant mesothelioma14q11.1-q13D14S283-D14S64See text
14q22-q24D14S258-D14S284
14q32?
Neuroblastoma14q12D14S80 (?)See text
14q23D14S63 (?)
14q32D14S62-D14S987
D14S17-D14S23
Lung carcinoma14q13D14S306 (?)See text
14q11-q24D14S80-D14S261
Gastrointestinal stromal tumours14q11-q12D14S283 (?)See text
14q23-q24.3D14S258 (?)
Non-papillary renal cell carcinoma14q24.2-qter? 80– 82
Uterine leiomyoma14q24.1D14S298-D14S540 83– 85
Primary head and neck squamous cell carcinoma14q13-q21D14S288-D14S269 90
14q31-q32.1D14S45-D14S78
Nasopharyngeal carcinoma14q11.2TCRD-D14S80/D14S283 91
14q12-q13D14S278-D14S288
14q32-qterD14S51-qter
Renal oncocytoma14q13-q21D14S288 (?) 92, 93
14q23-q24.4D14S63-D14S74
14q32D14S78-D14S826
Ovarian carcinoma14q12-q13D14S80-D14S70 94
14q32.1-q32.2D14S65-D14S267
Breast carcinoma14q31-q32D14S62-D14S5195 95
Soft tissue tumours14q11-qter? 96
Endometrial carcinoma14q11.2-qterTCRD-qter 97
Meningioma14q24.3-q31D14S55-D14S68 98
14q32.1-q32.2D14S45-D14S78
Stomach adenocarcinoma14q11-qter? 99