Table 2

Allele and genotype distribution of the −48 C/T polymorphism in early and late onset populations

NoAllele distribution (%)Genotype distribution (%)
CTCCCTTT
Early onset
AD cases176334 (0.93)24 (0.07)152 (0.86)24 (0.14)
Control254454 (0.89)54 (0.11)202 (0.79)50 (0.20)2 (0.01)
Late onset
AD cases105196 (0.93)14 (0.07)91 (0.87)14 (0.13)
Control209374 (0.90)44 (0.10)170 (0.81)34 (0.17)5 (0.02)
  • Number of subjects (frequency).