Table 1

X chromosome inactivation in breast cancer patients and controls

Age rangeSubjects with skewed X inactivation
(median)No (%)Total numberp value
Patients27–40 (38)4 (22)180.003
Controls20–403 (2)144
Patients27–45 (41)5 (13)400.009
Controls19–45 (33)1 (1)95
Patients27–65 (51)10 (7)1360.005
Controls19–65 (40)1 (0.7)138
Patients55–72 (63)7 (8)910.35
Controls55–72 (65)4 (4)91
Patients73–90 (78)6 (14)430.27
Controls73–93 (77)43 (21)202