Mean change of behavioural complaints in carriers and non-carriers 18 months after baseline
| DNA test | Carriers (n=35) Mean* (SD), range | Non-carriers (n=78) Mean* (SD), range | p† |
|---|---|---|---|
| *Higher score = fewer complaints (baseline minus follow up). | |||
| †Mean changes over time between the two groups (Mann-Whitney test). | |||
| ‡Significantly fewer complaints in carriers (Wilcoxon signed ranks test: p=0.007). | |||
| UHDRS behavioural | |||
| Sadness | 0.66 (3.09), −6–7 | 0.28 (3.15), −12–16 | 0.24 |
| Self-esteem‡ | 1.09 (2.67), −1–12 | 0.32 (2.04), −4–9 | 0.03 |
| Anxiety | 0.02 (4.22), −12–12 | 0.22 (3.62), −12–16 | 0.46 |
| Suicidal thoughts | 0 (0.87), −4–3 | 0.01 (0.34), −2–2 | 0.73 |
| Aggression | 0.29 (2.48), −8–9 | 0.28 (1.77), −4–9 | 0.55 |
| Irritable behaviour | 0.11 (3.03), −6–9 | 0.15 (2.66), −6–9 | 0.57 |
| Obsessions | −0.37 (2.09), −9–5 | 0.08 (2.29), −12–9 | 0.41 |
| Compulsions | 0.29 (3.2), −10–12 | −0.14 (2.36), −9–16 | 0.53 |