Comparison of autosomal dominant conditions with ocular and skeletal anomalies
| Clinical features | Present cases | Acroreno-ocular syndrome7 8 | Macular coloboma with type B brachydactyly9 10 | Oculodentodigital dysplasia11 12 | Pallister-Hall syndrome13 14 |
Kenny-Caffey syndrome type 215 16 | Acrofacial dysostosis 1, Nager type17 |
| Microphthalmia or coloboma | 2/3 | + | + | + | + | Hyperopia | − |
| Postaxial polydactyly | 2/3 | − | − | − | + | − | + |
| Delayed intramembranous ossification | 3/3 | − | − | − | − | + | − |
| Accessory nipples | 2/3 | − | − | − | − | − | − |
| Talipes equinovarus | 1/3 | − | − | − | − | − | − |
| Thumb and radial defects | 0/3 | + | + | − | + | − | + |
| Distal phalangeal hypoplasia | 0/3 | + | + | + | + | − | + |
| Renal anomalies | 0/3 | + | + | − | + | − | |
| Other | 0/3 | 1-150 | 1-151 | 1-152 | 1-153 | 1-154 | 1-160 |
↵1-150 Preaxial polydactyly.
↵1-151 Deafness, upper extremity 4, 5 syndactyly.
↵1-152 Preaxial polydactyly, upper extremity 4, 5 syndactyly, dental hypoplasia, spastic paraparesis, hypotelorism.
↵1-153 Hypothalamic hamartoblastoma, hypopituitarism, imperforate anus, mental retardation.
↵1-154 Hypocalcaemia, hypophosphataemia, short stature, macrocephaly, micro-orchidism.
↵1-160 Distinctive facies, micrognathia.