Group characteristics of 134 participants
| DNA test | Carriers (n=46) | Non-carriers (n=88) | p |
|---|---|---|---|
| *Chi-square test; †t test; ‡Mann-Whitney test. | |||
| §Seven DNA results not yet known at time of neuropsychological assessment (NPA). | |||
| ¶Two missing. | |||
| Gender, M/F | 16/30 | 40/48 | 0.23* |
| Age at NPA, mean (range), years | 39 (21–66) | 42 (18–64) | 0.16† |
| Education | |||
| Less than secondary school | 4 (9%) | 6 (7%) | |
| Secondary school | 29 (63%) | 56 (64%) | 0.78‡ |
| Higher than secondary school/university | 13 (28%) | 26 (30%) | |
| Number of CAG repeats, median (range) | 43 (39–51) | 19 (14–34) | |
| Age in years at DNA result, mean (range) | 39 (18–62) | 36 (18–62) | 0.09† |
| Time interval in months between DNA result and first NPA (n=127§), median (range) | 43 (1–60) | 36 (0–61) | 0.02‡ |
| History of depression, yes/no¶ | 14/30 | 18/70 | 0.15* |
| Use of neuroleptics | 0.15* | ||
| Antidepressive drugs | 2 (4%) | 4 (5%) | |
| Anxiolytic drugs | 3 (7%) | – | |