Table 2

Allele frequencies in wild type and mutant chromosomes

A		Exon 3 SNP^			Exon 8 SNP^			Exon 11 SNP^			Exon 17 SNP^
A		N	525		d18	N		525	d18		N	525	d18	N	525	d18
1	0.24			0.81	1.0	1.0	0.74		0.82	0.22		0.08
2	0.76	1.0	1.0	0.19			0.26	1.0	0.18	0.78	1.0	0.92
No	51	24	12	52	23	13	41	17	11	50	22	13

A denotes the different alleles; allele 1 represents the major allele and allele 2 the minor allele (see table 4).
N represents wild type chromosomes; 525 represents chromosomes containing the 525delT mutation; d18 represents chromosomes containing the del exon 18 mutation.
No denotes the number of individual chromosomes counted.