Table 3

Positive predictive value and relative sensitivity in families ascertained on the existence of multiple tumours in the proband child

Criteria on relatives Predictive value Relative sensitivity
None 21% (6/28)40% (6/15)
Very loose 42% (5/12)33% (5/15)
Loose 63% (5/8)33% (5/15)
Stringent 71% (5/7)33% (5/15)
Very stringent100% (3/3)20% (3/15)