Onset of disease manifestations in AFD carriers >18 years
| Disease manifestation | Mean age of onset (95% CI) | Total number of patients investigated |
| Neuropathic pain | 15 (11.13, 18.87) | 60 |
| CVA | 41.7 (15.3, 68.2) | 60 |
| TIA | 52 (43.89, 60.11) | 60 |
| Renal dialysis | 36 (35, 37) | 60 |
| Renal transplant | None | 60 |
The cohort examined in this study consisted of 60 obligate carrier females, mean age 44.9 years (95% CI 41.01, 48.79).