Table 1

Characteristics and clinical data from FAP family GE08

Subjects Clinical presentation1-150 1-152 Age at diagnosis polyps/cancer1-153 Number of adenomas Exon 14 mutation
II.1 1-151Symptomatic??NT
II.3 1-151Symptomatic??NT
III.1 1-151Symptomatic??NT
III.4 1-151Symptomatic??NT
III.5Symptomatic61/61>100Present
IV.1Symptomatic46>100Present
IV.2Call up440Absent
IV.3Call up420Absent
IV.4Symptomatic406Present
IV.5Call up360Absent
IV.6Call up340Absent
IV.9NK34NKNT
IV.10Symptomatic447Present
IV.11Call up360Absent
IV.12Call up400Absent
IV.13Call up380Present
IV.14Symptomatic34/34>100Present
IV.15Call up391Absent
IV.16Symptomatic36/36>100Present
IV.17NK32NKNT
IV.18NK31NKNT
IV.19NK29NKNT
IV.20Call up250Absent
V.1Call up150Present
V.2Call up130Absent
V.3NK11NKAbsent
V.4NK10NKAbsent
V.6NK11NKPresent
V.7NK10NKAbsent
V.8NK2NKNT

  • ↵1-150 Symptomatic, patients showing symptoms of FAP and/or CRC.

  • ↵1-151 Symptomatic, no data available.

  • ↵1-152 No extracolonic manifestations were present in affected subjects.

  • ↵1-153 Unaffected subjects and asymptomatic gene carriers, actual age, and age at DNA test are given.

  • Call up, called for endoscopic examination as at risk subjects; NK, not known; NT, not tested.