Table 3
Molecular classes of Angelman syndrome
Class
Molecular defect
Families
%
Patients
%
I
15q11-13 deletion
63
68
64
61
II
Uniparental disomy (UPD)
7
7
7
7
III
Imprinting defect (ID)
3
3
7
7
IV
UBE3A
mutation
10
11
15
14
V
Unknown
10
11
11
11