Table 1

Clinical, laboratory, and radiographic data from 15 patients with progressive diaphyseal dysplasia

		Patient
		III.5	III.7	III.8	III.10	III.11	IV.1	IV.2	IV.3	IV.4	IV.5	IV.6	IV.7	IV.9	IV.10	IV.12
Age at onset of symptoms (y)	30	20	20	15	21	15	14	3	10	10	8	5	18	13	2
Age at examination (y)	54	64	51	42	47	25	16	36	34	29	23	8	20	16	26
Pain in limbs	PMo	PMi	PMi	PMi	PMi	PMi	PMi	PMo	PMo	PMo	PMo	PMi	A	A	PS
Easy fatiguability	PMo	PMi	A	PMi	A	PMi	A	PMo	PMi	PMo	PMo	A	A	PMi	PMo
Headache	A	A	A	PMi	A	A	PMi	A	PMi	A	A	A	PMi	A	A
Poor appetite	A	A	A	PMi	A	PMi	A	A	A	A	A	A	A	A	PMi
Poor muscle mass	A	A	A	A	A	A	A	PMi	A	PMo	A	PMi	A	A	PMo
Waddling gait	PMi	PMi	A	A	A	PMi	A	PMi	PMi	PMo	PMo	A	A	A	PS
Radiographic bone changes	PMo	PS	PMo	PMo	PMi	PMo	PMi	PS	PS	PS	PS	PMi	PMi	PMi	PS
Haemoglobin (g/dl)	13.6	13.2	14.9	12.9	12.9	15.3	13.3	13.7	14.5	14.6	13.3	12.8	13.9	14.7	13.7
Erythrocyte sedimentation rate mm/h	14	28	1	3	11	9	11	13	16	15	6	11	10	4	16
Alkaline phosphatase (U/l)	27	42	81	24	33	28	20	35	52	57	203	105	46	71	97