Table 2

Mean allele ratio for Finnish founder mutation 1 using radiolabelled PCR specific for the normal and mutated allele, which are then size fractionated by agarose gel electrophoresis and analysed for intensities of mutant and wild type alleles

Sample Mean allele ratio Allele loss
11.19No
20.47Yes
30.48Yes
40.49Yes
5NDND
60.32Yes
  • ND, not determined.