Association between variant of STAT6 gene and atopic asthma in the Japanese population
| Phenotype | No of cases | 2964G/A genotype of STAT6 | |||
|---|---|---|---|---|---|
| AA+ AG | GG | Odds (95% CI) | p value | ||
| Controls | 00 | 91 | 9 | ||
| Asthma | |||||
| Adult atopic marked | 100 | 84 | 16 | 1.93 (0.79–4.69) | 0.134 |
| Adult atopic mild | 100 | 76 | 24 | 3.19 (1.40–7.08) | 0.0043 |
| Childhood atopic marked | 100 | 90 | 10 | 1.12 (0.42–2.93) | 0.809 |
| Intrinsic adult | 100 | 88 | 12 | 1.65 (0.68–4.00) | 0.376 |
| Low IgE | 265 | 224 | 41 | ||
| High IgE | 235 | 204 | 31 | 0.83 (0.50–1.37) | 0.469 |
| ASE(−) | 183 | 159 | 24 | ||
| ASE(+) | 317 | 270 | 47 | 0.87 (0.51–1.47) | 0.597 |
| Non-atopic | 167 | 147 | 20 | ||
| Atopic | 333 | 278 | 55 | 0.77 (0.44–1.31) | 0.180 |