Risk estimates for the likelihood of VHL disease given a patient presenting with a single ocular angioma for differing combinations of clinical and molecular information
| Other negative information | Age group (y) | |||
|---|---|---|---|---|
| <20 | 21–40 | 41–60 | >60 | |
| None | 0.30 | 0.30 | 0.30 | 0.30 |
| DNA | 0.11 | 0.11 | 0.11 | 0.11 |
| Systemic screening | 0.27 | 0.13 | 0.06 | 0.02 |
| Parental history | 0.19 | 0.13 | 0.09 | 0.09 |
| Parental history + systemic screening | 0.17 | 0.05 | 0.02 | 0.01 |
| DNA + parental history | 0.06 | 0.04 | 0.03 | 0.03 |
| DNA + systemic screening | 0.10 | 0.04 | 0.02 | 0.01 |
| DNA + systemic screening + parental history | 0.06 | 0.01 | <0.01 | <0.01 |