Estimates from previous work1–4 6 of the conditional probabilities of four clinical and molecular states given the presence of VHL disease for four age groups (see text)
| i= | Pr(Ci‖VHL) | Age group (y) | |||
|---|---|---|---|---|---|
| <20 | 21–40 | 41–60 | >60 | ||
| 1 | Pr(solitary ocular angioma‖VHL) | 0.20 | 0.20 | 0.20 | 0.20 |
| 2 | Pr(negative parental history‖VHL) | 0.54 | 0.34 | 0.24 | 0.24 |
| 3 | Pr(negative systemic screening‖VHL) | 0.90 | 0.35 | 0.15 | 0.05 |
| 4 | Pr(negative DNA screening‖VHL) | 0.27 | 0.27 | 0.27 | 0.27 |