Table 3

Candidate genes for human congenital cataract

Location Symbol Name
1p31-22CRYZCrystallin ζ
1q21-25CAE1, CX50Connexin 50
2q33-35CRYGACrystallin γA
2q33-35CRYGBCrystallin γB
2q33-35CRYGCCrystallin γC
2q33-35CRYGDCrystallin γD
2q33-35CRYGEP1Crystallin, γE pseudogene 1
2q33-35CRYGFP1Crystallin, γF pseudogene 1
2q34-36CRYGBA2Crystallin βA2
3q21-25CP49Phakinin
3CRYGSCrystallin γS
4q28-31PITX2/RIEG1RIG/PITX homeobox gene
6p25FREAC-7Forkhead related activator
6qCX43Connexin 43
10q25PITX3RIEG/PITX homeobox gene
11p13PAX-6PAX homeobox gene
11q21.1-23.2CRYA2Crystallin αB
12q13-14MIPMajor intrinsic protein, aquaporin
13q11-12CX46, CZPConnexin 46
16p13.11-12.3CRYMCrystallin μ
17q11.1-12CRYBA1Crystallin βA1
19q13.4LIM2Lens integral membrane protein 2
20CP115, LIFL-HFilensin
21q22.3CRYA1Crystallin αA
22q11.2-12.1CRYBB1Crystallin βB1
22q11.2-12.1CRYBB2Crystallin βB2
22q11.2-12.1CRYBB2PCrystallin βB2 pseudogene
22q11.2-12.1CRYBB3Crystallin βB3
22q11.2-12.1CRYBA4Crystallin βA4