The clinical features and mode of inheritance for all types of osteogenesis imperfecta are presented according to the classification of Sillence et al1
| OI type | Clinical features | Inheritance | ||
| OI type I (mild) | Normal or near normal stature with little or no deformity | AD | ||
| Variable number of fractures | ||||
| Distinctly blue sclerae throughout life | ||||
| Hearing loss in about 50% of cases | ||||
| OI type II (lethal) | Lethal in perinatal period or in utero | AD (new mutations) | ||
| Severe dwarfism with marked bowing and deformities of the extremities | AR (rare) | |||
| Extreme bone fragility | ||||
| OI type III (severely deforming) | Progressively deforming bones | AD | ||
| Very short stature | AR (uncommon) | |||
| Dentinogenesis imperfecta common | ||||
| OI type IV (moderately severe) | Variable short stature | AD | ||
| Mild to moderate bone deformity Variable fracture rate Scoliosis/lordosis in some patients | ||||
| Dentinogenesis imperfecta common | ||||
AD: autosomal dominant; AR: autosomal recessive.