Table 2

Percentage of the study population showing specific signs and complications of FRDA in three series6 20 51

Harding6 Dürr et al20 Delatycki et al51
Gait ataxia100100
Limb ataxia9999100
Lower limb muscle weakness8867
Diminished vibration sense737888
Pes cavus555574
Dysarthria979195
Extensor plantar responses897974
Cardiomyopathy66* 6365
Diabetes10328
Scoliosis796078
Reflexes LL0.9122
Sphincter disturbance2341
Decreased visual acuity1813
Hearing loss813
  • LL = lower limbs. — = not reported. * = Based on abnormal ECG excluding 9.6% where ECG changes were described as insignificant.