Frequency of microsatellite instability (MSI) positive tumours and hMSH2 and hMLH1 germline mutations in early onset colorectal cancer patients
| No of patients | MSI positive (%) | hMSH2, hMLH1 germline mutations (%) | % of mutations in MSI positive tumours | |
|---|---|---|---|---|
| Non-HNPCC | 38 | 13 (38)4-150 | 3 (8) | 23 |
| HNPCC | 16 | 12 (75) | 6 (37) | 50 |
| Total | 54 | 25 (50)4-150 | 9 (17) | 36 |
↵4-150 Four patients not tested.