Table 2

Distribution of RET mutations in MEN 2

Codon NoPhenotypeFrequency2-150
609MEN 2A<0.01
FMTC0.04
611MEN 2A0.02
FMTC<0.01
618MEN 2A0.03
FMTC0.30
620MEN 2A0.06
FMTC0.21
630FMTC<0.01
634MEN 2A0.87
FMTC0.26
768FMTC0.08
790FMTC<0.01
791FMTC<0.01
804FMTC0.03
883MEN 2B0.05
891FMTC<0.01
918MEN 2B0.94
  • 2-150 Only mutations found in multiple independent families are included.