Table 3

DNA probes used for characterisation of the tetrasomic region of chromosome 21

Probe names	Gene markers	Mapping location^3-151	Test results (copy number)
E9 (cosmid)	D21S16	21q11.2	3
B76H7^3-150	D21S11/S1	21q11.2-21.1	4
B839E9		D21S383-S385	21q21.1		4
		Y221B7^3-150
B427H6		D21S18-S281	21q21.1		2^3-152
		Y193G12
APP (cosmid)	APP	21q21.2	2
B96E9		D21S303-S129	21q21.2-21.3		2
		Y760H5
B8B3	D21S390-S262	21q21.2-21.3	2
5F4	D21S217-S299	21q21.3	2
B19C7		D21S58-S216	21q21.3		2
		Y876D4
B417D6		D21S296-S82	21q22.1		2
		Y62G5
ICRF0251 (cosmid)	D21S299 (JG108)	21q22.1	2
138H8 (cosmid)		D21S82-S302	21q22.3		2
		Y814C1

↵3-150 B = BAC, Y = YAC.
↵3-151 The probes have been ordered according to their cytogenetic mapping location.
↵3-152 The two signals from this and subseqent probes were located on the q arms of the normal chromosomes 21 of the proband.