Table 1

Pairwise lod scores of chromosomes 3p, 4q, and 10q DNA markers in a Belgian ADPEO family. The 3p DNA markers are ordered from telomere to centromere and the 10q and 4q markers from centromere to telomere conform with their position on the genetic map (Whitehead Institute,http://www-genome.wi.mit.edu/cgi-bin/contig/physmap). For each marker the genetic distance excluded (exclusion limit) was calculated from the recombination distance at Z=−2

Marker		Lod score at θ=
Marker		0.00	0.01	0.05	0.10	0.20	0.30	0.40	Exclusion limit
D3S3666	−3.59	−1.31	−0.48	−0.14	0.10	0.11	0.04	0.01
D3S3553	−7.76	−3.02	−1.49	−0.84	−0.28	−0.08	−0.01	0.03
D3S1300	−3.60	−1.02	−0.39	−0.18	−0.05	−0.02	−0.01	0.00
D3S1312	−7.96	−2.87	−1.54	−1.03	−0.59	−0.36	−0.17	0.04
D3S1600	−3.39	−1.22	−0.60	−0.38	−0.20	−0.12	−0.05	0.00
D3S3571	−12.31	−4.63	−2.60	−1.78	−0.98	−0.51	−0.20	0.09
D10S1750	−7.12	−2.05	−0.79	−0.35	−0.06	0.00	0.01	0.01
D10S1773	−11.36	−4.23	−2.21	−1.40	−0.68	−0.33	−0.12	0.04
D10S1731	−15.89	−5.79	−3.06	−1.95	−0.92	−0.42	−0.14	0.10
D10S187	−11.48	−4.13	−2.10	−1.28	−0.56	−0.24	0.08	0.06
D10S190	1.11	1.09	0.97	0.82	0.52	0.26	0.08
D10S1757	−6.82	−2.00	−0.73	−0.30	0.02	0.03	0.02	0.01
D10S1483	−3.66	−0.98	−0.35	−0.13	0.01	0.04	0.03	0.01
D10S587	−7.34	−2.56	−1.19	−0.65	−0.19	−0.02	−0.02	0.04
D10S1723	−11.36	−4.50	−2.41	−1.53	−0.72	−0.33	0.11	0.08
D10S1656	−7.82	−3.10	−1.70	−1.09	−0.52	−0.23	−0.07	0.04
D10S186	−2.62	0.04	0.58	0.68	0.58	0.35	0.12	0.00
D10S1782	−7.22	−2.40	−1.09	−0.58	−0.18	−0.03	0.01	0.03
D4S1554	−11.57	−3.96	−1.96	−1.18	−0.53	−0.24	−0.09	0.05
D4S2924	−7.39	−2.49	−1.18	−0.68	−0.28	−0.12	−0.05	0.03
D4S2299	−11.48	−4.36	−2.34	−1.52	−0.76	−0.37	−0.13	0.07