Odds ratios and 95% confidence intervals of 5,10-methylenetetrahydrofolate reductase (MTHFR) and methione synthase (MS) genotypes in fetuses with NTDs (cases) and controls
| MTHFR genotype | MS genotype | NTDs (cases) | Controls | Odds ratio | 95% confidence interval | |
|---|---|---|---|---|---|---|
| Ala/Ala | Asp/Asp | 32 | 53 | 1.0 | ||
| Asp/Gly | 8 | 9 | 1.5 | 0.5–4.2 | ||
| Gly/Gly | 0 | 1 | — | — | ||
| Ala/Val | Asp/Asp | 22 | 10 | 1.0 | ||
| Asp/Gly | 7 | 1 | 3.2 | 0.3–29.4 | ||
| Gly/Gly | 0 | 0 | — | — | ||
| Val/Val | Asp/Asp | 5 | 1 | 1.0 | ||
| Asp/Gly | 3 | 1 | ||||
| Gly/Gly | 0 | 0 | — | — | ||