Table 2

Odds ratios and 95% confidence intervals of 5,10-methylenetetrahydrofolate reductase (MTHFR) and methione synthase (MS) genotypes in fetuses with NTDs (cases) and controls

MTHFR
genotype
MS genotypeNTDs (cases)ControlsOdds ratio95% confidence interval
Ala/AlaAsp/Asp32531.0
Asp/Gly891.50.5–4.2
Gly/Gly01
Ala/ValAsp/Asp22101.0
Asp/Gly713.20.3–29.4
Gly/Gly00
Val/ValAsp/Asp511.0
Asp/Gly31
Gly/Gly00