Table 1

Odds ratios and 95% confidence intervals of 5,10-methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MS) genotypes in fetuses with NTDs (cases) and controls

GenotypeNTDs (cases)ControlsOdds ratio95% confidence interval
MTHFR
 Ala/Ala43/82 (52%)63/76 (83%)1.0
 Ala/Val30/82 (37%)11/76 (14%)4.01.8–8.8
 Val/Val9/82 (11%)2/76 (3%)6.61.3–24.9
MS
 Asp/Asp59/77 (77%)70/84 (83%)1.0
 Asp/Gly18/77 (23%)13/84 (14%)1.60.7–3.6
 Gly/Gly0/77 (0%)1/84 (1%)