Summary. Analysis of chromosome 21 in preimplantation embryos from two couples at high risk of Down syndrome pregnancy undergoing PGD
| Parental karyotype | Normal5-150 | Diploid mosaic | Aneuploid/ mosaic |
|---|---|---|---|
| (1) Gonadal mosaic for trisomy 21 | |||
| Cycle 1 | 0 | 0 | 2 |
| Cycle 2 | 2 | 0 | 3 |
| (2) 46,XX,t(6;21)(q13;q22.3) | |||
| Cycle 1 | 1 | 1 | 5 |
| Cycle 2 | 0 | 0 | 2 |
| Combined totals 16 (100%) | 3 (19%) | 1 (6%) | 12 (75%) |
↵5-150 Normal for chromosome 21.