Table 1

Number of ACTANE families by source and number affected

SourceNo of cases per family
UK3131 466
Canada3934 780
Texas 3 6 312
Australia1322 136
Norway 2 2 2 6
EU Biomed 3 3 1 7
  • The criteria for inclusion in ACTANE are two related PC family members (first/second degree) where one case is <65 years at PC diagnosis, or ⩾3 or more PC cases in a cluster at any age.

  • Cases were verified by patient history and/or medical record/pathology report in the UK, Canada, Texas, and EU, and by cancer registration and medical records in Norway and Australia.