Table 2

Tests for pairwise linkage disequilibrium at four intra-MLH1 loci and four loci closely linked to MLH1

D3S1561 D3S1277 Exon 8 A/G BAT-21 D3S1611 IVS14 A/G D3S1298 D3S3527
D3S1561 * +−−+−++
D3S1277+ * −−+−++
Ex 8 A/G−− * ++ ++ ++ +−
BAT-21−− ++ * ++ ++ +−
D3S1611++ ++ ++ * ++ ++
IVS14 A/G−− ++ ++ ++ * +−
D3S1298++++++ * +
D3S3527++−−+−+ *

  • +: linkage disequilibrium significant at exact p values <0.05.

  • ++: linkage disequilibrium significant at p values <<0.0001, χ2 test values >94 with 1–5 degrees of freedom.