Table 1

GFRα-1 polymorphisms in HSCR patient and control DNA samples

Amino acid change		Nucleotide		Frequency
Amino acid change		Nucleotide		HSCR	Control
	−193	C	0.98	0.93
		G	0.02	0.07
	−106	G	0.96	0.86
		A	0.04	0.14
	−78	T	0.69	0.68
		C	0.31	0.32
D14A	41	A	>0.99	0.99
		C	<0.01	0.01
Y85N	253	T	0.98	0.96
		A	0.02	0.04
N86D	256	A	>0.99	0.99
		G	<0.01	0.01
N179N	537	T	0.6	0.59
		C	0.4	0.41
	IVS5+21	G	0.92	0.82
		A	0.08	0.18
Q350H	1050	G	1.0	0.99
		T	0	0.01
T361A	1081	A	0.93	0.88
		G	0.07	0.12