Table 1

Results of sequencing and haplotype analysis in 13 patients from seven SCA2 families

Family	Case	Relation to other cases	Repeat size	Config of poly	D12S84	D12S105	D12S1672	D12S1333	D12S354	D12S79
A	1 M	Father of A-2	37, 37	Normal	10	2	4	7	3	8
	2 F	Proband	44	Normal	10	2	4	7	3	8
B	1 F	Proband	51, 53	Normal	8 or 10	1 or 2	2 or 3	2 or 6	6	2 or 3
C	1 F	Proband	43, 44, 46	Normal	9 or 10	1 or 2	1 or 2	5 or 6	4 or 6	3 or 5
D	1 F	Older sister of D-2	37	CCG	8	2	2	2	1	5
	2 F	Proband	41, 42	CCG	8	2	2	2	1	5
E	1 M	Father of E-2	37, 37, 37	CCG	3	2	2	2	1	3 or 7
	2 M	Proband	44	CCG	3	2	2	2	1	3 or 7
F	1 F	Older sister of F-2	41	CCGCCG	7	2	2	2	6	5
	2 M	Uncle of F-3	42, 42, 43	CCGCCG	7	2	2	2	6	5
	3 F	Proband	51, 51	CCGCCG	7	2	2	2	6	5
G	1 F	Older sister of G-2	37, 38, 40	CCGCCG	7	2	2	2 or 6	3 or 6	5
	2 M	Proband	36	CCGCCG	7	2	2	2 or 6	3 or 6	5

Repeat size means the number of long CAG repeats in each subclone of the expanded alleles.
Config of poly: configuration of polymorphisms. F: female. M: male.