Infant methionine synthase genotype and risk for spina bifida
| Genotype | Cases | Controls | Odds ratio | 95% confidence interval | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| No | % | No | % | ||||||||
| Overall | |||||||||||
| GG | 1 | 1 | 7 | 4 | 0.23 | 0.05–1.9 | |||||
| AG | 30 | 32 | 49 | 31 | 0.99 | 0.58–1.7 | |||||
| AA | 64 | 67 | 104 | 65 | Reference | — | |||||
| Non-Hispanic Whites | |||||||||||
| GG | 1 | 3 | 3 | 5 | 0.60 | 0.11–5.6 | |||||
| AG | 10 | 31 | 16 | 28 | 1.1 | 0.44–2.9 | |||||
| AA | 21 | 66 | 38 | 67 | Reference | — | |||||
| Hispanic Whites | |||||||||||
| GG | 0 | 0 | 4 | 4 | 0 | — | |||||
| AG | 20 | 32 | 33 | 32 | 0.93 | 0.48–1.8 | |||||
| AA | 43 | 68 | 66 | 64 | Reference | — | |||||