Locus | Allele | Patients (frequency) | Controls (frequency) | χ2 | p | D | δ |
---|---|---|---|---|---|---|---|
Northern European | |||||||
D12S1332 | 5 | 7/17 (0.41) | 7/70 (0.10) | 9.85 | 0.0017 | 0.34 | 0.34 |
6 | 5/17 (0.29) | 40/70 (0.57) | 4.21 | 0.0401 | 0.22 | −0.65 | |
D12S1672 | 5 | 7/14 (0.50) | 3/77 (0.04) | 21.24 | <0.0001 | 0.48 | 0.48 |
7 | 5/14 (0.36) | 54/77 (0.70) | 4.73 | 0.030 | 0.23 | −1.13 | |
D12S1333 | 2 | 6/17 (0.35) | 9/66 (0.14) | 4.28 | 0.038 | 0.23 | 0.24 |
8 | 8/17 (0.47) | 3/66 (0.04) | 17.71 | <0.0001 | 0.46 | 0.45 | |
Whole population | |||||||
D12S1332 | 5 | 8/23 (0.35) | 10/104 (0.10) | 9.8 | 0.0017 | 0.28 | 0.28 |
6 | 9/23 (0.39) | 48/104 (0.46) | 0.14 | NS | — | — | |
D12S1672 | 5 | 7/18 (0.39) | 8/101 (0.08) | 13.30 | 0.0003 | 0.33 | 0.34 |
7 | 6/18 (0.33) | 66/101 (0.65) | 6.55 | 0.0105 | 0.23 | −0.91 | |
D12S1333 | 2 | 8/22 (0.36) | 9/96 (0.09) | 10.57 | 0.0011 | 0.30 | 0.30 |
8 | 11/22 (0.50) | 4/96 (0.04) | 29.88 | 0.0000 | 0.50 | 0.48 | |
D12S1332−D12S1672−D12S1333 haplotype | |||||||
6−7−2 | 5/16 (0.31) | 4/46 (0.09) | 3.21 | NS | |||
5−5−8 | 6/17 (0.35) | 0/50 (0.00) | 15.29 | <0.0001 | 0.48 | 0.35 |
NS = not significant.