Comparison of the IP and DKC phenotypes affecting ectodermal tissues and the haemopoietic system
| Incontinentia pigmenti (IP) | Dyskeratosis congenita (DKC) | |
|---|---|---|
| Skin | ||
| Reticulate hyperpigmentation | + (late stage) | + (early stage) |
| Hypopigmentation | + (reticulate or linear) | + (scattered macules) |
| Alopecia | + (scarring) | + (non-scarring) |
| Epidermal atrophy | + (late stage) | + |
| Pigment incontinence | + | + |
| Teeth | ||
| Hypodontia | + (prominent) | + (occasional) |
| Eyes | ||
| Retinal involvement | + (retinal detachment, vascular proliferation) | − |
| Epiphora | + (rare, one case) | + (frequent) |
| Haemopoietic system | ||
| Pancytopenia | − | + |
| Bone marrow failure | − | + |