TY - JOUR T1 - Response to correspondence on “Phenocopies in BRCA1 and BRCA2 families: evidence for modifier genes and implications for screening” JF - Journal of Medical Genetics JO - J Med Genet SP - e88 LP - e88 DO - 10.1136/jmg.2007.051722 VL - 44 IS - 8 AU - A Smith AU - M C Boyd AU - M Bulman AU - A Shenton AU - F Lalloo AU - D G R Evans AU - A Moran AU - R Iddenden AU - L Smith AU - E R Woodward AU - E R Maher Y1 - 2007/08/01 UR - http://jmg.bmj.com/content/44/8/e88.abstract N2 - We wish to reply to the interesting comments concerning our paper on phenocopies in families positive for mutations in BRCA1/2 genes since its electronic publication in October 2006.1 We understand the reservations about changing practice in reassuring individuals who test negative for a family mutation based on one largely retrospective analysis of families, and clearly there is a need to confirm our results in other large series. We were particularly careful to obviate … ER -