TY - JOUR T1 - From errant enzymes to colon cancers JF - Journal of Medical Genetics JO - J Med Genet SP - 488 LP - 488 DO - 10.1136/jmg.39.7.488 VL - 39 IS - 7 A2 - , Y1 - 2002/07/01 UR - http://jmg.bmj.com/content/39/7/488.abstract N2 - The suggestion that some colorectal cancers (CRCs) develop by a methylation pathway has been given support by a genetic study of 500 patients in Australia. The findings support the view that key enzymes in the metabolism of folate and methyl groups, which affect DNA methylation, influence predisposition to CRCs, particularly … ER -