PT - JOURNAL ARTICLE AU - S A Farrell AU - A M Summers AU - L Dallaire AU - J Singer AU - Jo-Ann M Johnson AU - R D Wilson TI - Club foot, an adverse outcome of early amniocentesis: disruption or deformation? AID - 10.1136/jmg.36.11.843 DP - 1999 Nov 01 TA - Journal of Medical Genetics PG - 843--846 VI - 36 IP - 11 4099 - http://jmg.bmj.com/content/36/11/843.short 4100 - http://jmg.bmj.com/content/36/11/843.full SO - J Med Genet1999 Nov 01; 36 AB - An association between the occurrence of club foot and early amniocentesis has been reported. The largest of these randomised studies was the Canadian Early and Mid-Trimester Amniocentesis Trial. Data describing the neonatal outcome, focusing on this association, are presented. Possible mechanisms for the association and the implications for the development of club foot are discussed.