TY - JOUR T1 - A syndrome of immune complex glomerulonephritis and ophthalmic abnormalities JF - Journal of Medical Genetics JO - J Med Genet SP - 641 LP - 644 DO - 10.1136/jmg.36.8.641 VL - 36 IS - 8 AU - Iradj Amirlak AU - Sharda G Sabnis AU - Lihadh Al-Gazali AU - Yousef M Abdulrazzaq Y1 - 1999/08/01 UR - http://jmg.bmj.com/content/36/8/641.abstract N2 - Two sibs (one male and one female) suffering from a combination of immune complex glomerulonephritis and various ophthalmologic disorders are presented. The two cases belong to a family in which the parents are not related and seven sibs are affected, three females and a male with the combination, and three males with severe ophthalmological changes and proteinuria. Clinically, case 2 had only ophthalmological manifestations but renal biopsy findings were similar to those of case 1, which could mean that all the others with eye abnormalities also had renal disease. Although there are several reports of combinations of eye and renal disorders, the sibs reported here do not fit into any of the known syndromes. ER -