RT Journal Article
SR Electronic
T1 A syndrome of immune complex glomerulonephritis and ophthalmic abnormalities
JF Journal of Medical Genetics
JO J Med Genet
FD BMJ Publishing Group Ltd
SP 641
OP 644
DO 10.1136/jmg.36.8.641
VO 36
IS 8
A1 Amirlak, Iradj
A1 Sabnis, Sharda G
A1 Al-Gazali, Lihadh
A1 Abdulrazzaq, Yousef M
YR 1999
UL http://jmg.bmj.com/content/36/8/641.abstract
AB Two sibs (one male and one female) suffering from a combination of immune complex glomerulonephritis and various ophthalmologic disorders are presented. The two cases belong to a family in which the parents are not related and seven sibs are affected, three females and a male with the combination, and three males with severe ophthalmological changes and proteinuria. Clinically, case 2 had only ophthalmological manifestations but renal biopsy findings were similar to those of case 1, which could mean that all the others with eye abnormalities also had renal disease. Although there are several reports of combinations of eye and renal disorders, the sibs reported here do not fit into any of the known syndromes.