PT  - JOURNAL ARTICLE
AU  - Iradj Amirlak
AU  - Sharda G Sabnis
AU  - Lihadh Al-Gazali
AU  - Yousef M Abdulrazzaq
TI  - A syndrome of immune complex glomerulonephritis and ophthalmic abnormalities
AID  - 10.1136/jmg.36.8.641
DP  - 1999 Aug 01
TA  - Journal of Medical Genetics
PG  - 641--644
VI  - 36
IP  - 8
4099  - http://jmg.bmj.com/content/36/8/641.short
4100  - http://jmg.bmj.com/content/36/8/641.full
SO  - J Med Genet1999 Aug 01; 36
AB  - Two sibs (one male and one female) suffering from a combination of immune complex glomerulonephritis and various ophthalmologic disorders are presented. The two cases belong to a family in which the parents are not related and seven sibs are affected, three females and a male with the combination, and three males with severe ophthalmological changes and proteinuria. Clinically, case 2 had only ophthalmological manifestations but renal biopsy findings were similar to those of case 1, which could mean that all the others with eye abnormalities also had renal disease. Although there are several reports of combinations of eye and renal disorders, the sibs reported here do not fit into any of the known syndromes.