TY - JOUR T1 - Townes-Brocks syndrome JF - Journal of Medical Genetics JO - J Med Genet SP - 89 LP - 93 DO - 10.1136/jmg.36.2.89 VL - 36 IS - 2 AU - Cynthia M Powell AU - Ron C Michaelis Y1 - 1999/02/01 UR - http://jmg.bmj.com/content/36/2/89.abstract N2 - Townes-Brocks syndrome (TBS) is an autosomal dominant disorder with multiple malformations and variable expression. Major findings include external ear anomalies, hearing loss, preaxial polydactyly and triphalangeal thumbs, imperforate anus, and renal malformations. Most patients with Townes-Brocks syndrome have normal intelligence, although mental retardation has been noted in a few. ER -